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brain tissue structural disorder using PWS.png

Brain tissue structural disorder using PWS

Histone molecular specific structural disorder by confocal IPR.png

Histone molecular-specific structural disorder by confocal-IPR

Online Google Scholar:

http://scholar.google.com/citations?user=WVU2BLYAAAAJ&hl=en

 

Published Refereed Journal Papers (Journal Publications: 62, Conference Proceeding:15)

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  1. Prakash Adhikari, Pradeep Shukla, Fatemah Alharthi, Shiva Bhandari, Radhakrishna Rao, and Prabhakar Pradhan. “Photonics probing of pups’ brain tissue and molecular specific nuclear nanostructure alterations due to fetal alcoholism via light scattering/localization approaches.”  To be appeared in the Journal of Biomedical Optics (2022).

  2. Liam Elkington, Prakash Adhikari, and Prabhakar Pradhan. "Fractal Dimension Analysis to Detect the Progress of Cancer Using Transmission Optical Microscopy." Biophysica 2, no. 1 (2022): 59-69.

  3. D. Roy, B. Jenkins, A. Ali, J. R. Herschmann, M. Harris, M. Zamadar, L. Simington, P. Adhikari, P. Pradhan, Bidisha Sengupta. "Multi-component redox system for selective and potent antineoplastic activity towards ovarian cancer cells." Biochemical and biophysical research communications (BBRC) 592, 38-43 (2022)

  4. Prabhakar Pradhan, "Phase Statistics of Light/Photonic Wave Reflected from One-Dimensional Optical Disordered Media and Its Effects on Light Transport Properties." Photonics 8, 485 (2021).

  5. Alexander Punnoose, Shirsendu Nanda, and Prabhakar Pradhan. "Reflectance statistics from a thin weakly disordered optical media: application to detection of structural alterations in cells/tissues." Optics Express 29, no. 26 (2021): 43612-43625.

  6. Prakash Adhikari, Pradeep K. Shukla, Fatemah Alharthi, Radhakrishna Rao, and Prabhakar Pradhan. “Photonic technique to study the effects of probiotics on chronic alcoholic brain cells by quantifying their molecular specific structural alterations via confocal imaging.” Journal of Biophotonics, e202100247 (2021).

  7. Mehedi Hasan, Pradeep K. Shukla, Shirsendu Nanda, Prakash Adhikari, Radhakrishna Rao, and Prabhakar Pradhan. "Photonic probing of structural alterations in DNA specific mass density fluctuations in nuclei due to total body irradiation (TBI) via confocal imaging." OSA Continuum 4, 569-578 (2021).

  8. Adhikari, Prakash, Mehedi Hasan, Vijayalakshmi Sridhar, Debarshi Roy, and Prabhakar Pradhan. "Studying nanoscale structural alterations in cancer cells to evaluate ovarian cancer drug treatment, using transmission electron microscopy imaging." Physical biology 17, 036005(2021).

  9. B. Sengupta, P. Adhikari, E. Mallet, R. Havner, and P. Pradhan, "Spectroscopic Study on Pseudomonas Aeruginosa Biofilm in the Presence of the Aptamer-DNA Scaffolded Silver Nanoclusters." Molecules 25, 3631(2020).

  10. E. Avery, S. Nanda, B. Regmi, P. Sahay, and P. Pradhan. "Numerical study of the degree of light scattering strength versus fractal dimension in strong to weak 2D and 3D disordered fractal optical media." OSA Continuum 3, 844-853 (2020).

  11. P. Adhikari, M. Hasan, V. Sridhar, D. Roy, D., and P. Pradhan, “Studying nanoscale structural alterations in cancer cells to evaluate ovarian cancer drug treatment, using transmission electron microscopy imaging.” Physical Biology, 17, 036005 (2020).

  12. P. Adhikari, Prashanth KB Nagesh, Fatemah Alharthi, Subhash C. Chauhan, Meena Jaggi, Murali M. Yallapu, and Prabhakar Pradhan. "Optical detection of the structural properties of tumor tissue generated by xenografting of drug-sensitive and drug-resistant cancer cells using partial wave spectroscopy (PWS)." Biomedical Optics Express 10, 6422-6431 (2019)

  13. S. Bhandari, P. Shukla, H. M. Almabadi, P. Sahay, R.K. Rao, and P. Pradhan, “Optical study of stress hormone-induced nanoscale structural alteration in the brain using partial wave spectroscopic (PWS) microscopy,” Journal of Biophotonics, 12, 201800002 (2019).

  14. S. Bhandari, S. Choudannavar, E. R. Avery, P. Sahay, and P. Pradhan, “Detection of colon cancer stages via fractal dimension analysis of optical transmission imaging of tissue microarrays (TMA).” Biomedical Physics & Engineering Express 4, 065020 (2018).

  15. H. M. Almabadi, P. Nagesh, P. Sahay, S. Bhandari, E. C. Eckstein, M. Jaggi, S. C. Chauhan, M Yallapu and P Pradhan, “Optical study of chemotherapy efficiency in cancer treatment via intracellular structural disorder analysis using partial wave spectroscopy,” Journal of Biophotonics 11, e201800056 (2018).

  16. P. Sahay, A. Ganju, H. M. Almabadi, H.M. Ghimire, M. M. Yallapu, O. Skalli, M. Jaggi, S.C. Chauhan, and P.  Pradhan, “Quantification of photonic localization properties of targeted nuclear mass density variations: application in cancer stage detection.” Journal of Biophotonics 11, e201700257 (2017).

  17. [This article was highlighted in Physics World news by the Institute of Physics (IOP, UK):  https://physicsworld.com/a/photonic-technique-eases-cancer-staging/]

  18. P. Sahay, H. M. Almabadi, H.M. Ghimire, O. Skalli, and P. Pradhan, "Light localization properties of weakly disordered optical media using confocal microscopy: application to cancer detection,"Optics Express 13, 15428-15440 (2017).                   

  19. [This article appeared as a Spotlight on Optics by the Optical Society of America (OSA):     https://www.osapublishing.org/spotlight/summary.cfm?URI=oe-25-13-15428]

  20. P. Pradhan, D.J. Park, I. Capoglu, H Subramanian, D. Damania, L. Cherkezyan, A. Taflove, V. Backman, "Reflection statistics of weakly disordered optical medium when its mean refractive index is different from an outside medium," Optics Communications 393, 185-190 (2017).

  21. P. Sahay, P. K. Shukla, H. M. Ghimire, H. M. Almabadi, V. Tripathi, S. K. Mohanty, R. K. Rao, and P. Pradhan, "Quantitative analysis of nanoscale intranuclear structural alterations in hippocampal cells in chronic alcoholism via transmission electron microscopy imaging," Physical Biology 14, 026001-7 (2017).

  22. S. Khan, M. Sikander, M. C. Ebeling, A. Ganju, S. Kumari, M Yallapu, B. B. Hafeez, T. Ise, S. Nagata, N. Zafar, S. W. Behrman, J.Y. Wan, H. M. Ghimire, P. Sahay, and P. Pradhan, S. C Chauhan, M. Jaggi, "MUC13 interaction with receptor tyrosine kinase HER2 drives pancreatic ductal adenocarcinoma progression," Oncogene 36 (Nature Publication), 1-10 (2016).

  23. B. Black, V. Vishwakarma, K. Dhakal, S. Bhattarai, P. Pradhan, A. Jain, Y. Kim, S.  Mohanty, "Spatial temperature gradients guide axonal outgrowth,"   Scientific Reports 6 (Nature Publications), 29876 (2016).

  24. D. J. Park, P. Pradhan, and V. Backman, "Enhancing the sensitivity of mesoscopic light reflection statistics in weakly disordered media by interface reflections," International Journal of Modern Physics B 30, 165015 (2016).

    1. J. Radosevich, J. D. Rogers, I. R. Çapoglu, N. N. Mutyal, P. Pradhan, and V.  Backman, “Open source software for electric field Monte Carlo simulation of coherent backscattering in biological media containing birefringence,” Journal of Biomedical Optics 17, 115001-115013 (2012).

  25. D. Damania, H. Roy, H. Subramanian, D. Weinberg, D. Rex, M. Goldberg, J. Muldoon, Y. Zhu, L. Bianchi, D. Shah, P. Pradhan, M. Borkar, H. Lynch, and V. Backman, “ Nanocytology of rectal colonocytes to assess risk of colon cancer based on field cancerization,” Cancer Research 72, 2720-2727 (2012).

  26. P. Pradhan, D. Damania, H. M. Joshi, V. Turzhitsky, H. Subramanian, H. K. Roy, A. Taflove, V. P. Dravid, and V. Backman, “Quantification of nanoscale density fluctuations by electron microscopy: probing cellular alterations in early carcinogenesis,” Physical Biology 8, 026012-026020 (2011).

  27. J. S. Kim, P. Pradhan, V. Backman, and I. Szleifer, “Influence of chromosome density variations on the increase in nuclear disorder strength in carcinogenesis,” Physical Biology 8, 015004-015009 (2011).

  28. J. D. Rogers, V. Stoyneva, V. Turzhitsky, N. N. Mutyal, P. Pradhan, I. R. Capoglu, and V. Backman, "Alternate formulation of enhanced backscattering as phase conjugation and diffraction: derivation and experimental observation," Optics Express 19, 11922-11931 (2011).

  29. P. Pradhan, D. Damania, H. M. Joshi, V. Turzhitsky, H. Subramanian, H. K. Roy, A. Taflove, V. P. Dravid, and V. Backman, "Quantification of Nanoscale Density Fluctuations using Electron Microscopy: Light Localization Properties of Biological Cells." Applied Physics Letters 97, 243704-243706 (2010).

  30. H. K. Roy, H. Subramanian, D. Damania, T. Hensing, D. Ray, A. Bogojevic, P. Pradhan, J. Rogers, N. Hasabou, I. Caopglu, and V. Backman, “Optical Detection of Buccal Epithelial Nano-Architectural Alterations in Patients Harboring Lung Cancer: Implications for Screening,” Cancer Research 70, 7748-7754 (2010).

  31. D. Damania, H. Subramanian, A. K. Tiwari, Y. Stypula, D. Kunte, P. Pradhan, H. K. Roy, and V. Backman, “Role of Cytoskeleton in Controlling the Disorder Strength of Cellular Nanoscale Architecture,” Biophysical Journal 99, 989-996 (2010).

  32. H. Subramanian, P.  Pradhan, Y. Liu, I. Capoglua, J. Rogers, H. K. Roy, and V. Backman, "Partial wave microscopic spectroscopy detects subwavelength refractive index fluctuations: an application to cancer diagnosis," Optics Letters 34, 518-520 (2009).

  33. H. Subramanian, H. K. Roy, P. Pradhan, M. J. Goldberg, R.E. Brand, C. Sturgis, T. Hensing, D. Ray, J. Chang, J. Mohammed, and V. Backman, "Partial Wave Spectroscopic Microscopy for Detection of Nanoscale Alterations of Field Carcinogenesis," Cancer Research 69, 5357-5363 (2009).

  34. H.K. Roy, V. Turzhitsky, Y. Kim, M. Goldberg, P. Watson, J. Rogers, A. Gomes, A. Kromine, R. Brand, M. Jameel, N. Hasabou, P. Pradhan, and V. Backman, "Association between Rectal Optical Signatures and Colonic Neoplasia: Potential Applications for Screening," Cancer Research 69, 4476-4483 (2009). 

  35. P.  Pradhan, G. C. Cardoso, and M.S. Shahriar, "Suppression of the Bloch-Siegert Oscillation Induced Error in Qubit Rotations via the Use of Off-Resonance Raman Excitation," Journal of Physics B: Atomic, Molecular and Optical Physics 42, 065501-065507 (2009).

  36. H. Subramanian, P. Pradhan, Y. Liu, I. Capoglu, X. Li, J. Rogers, A. Heifetz, D. Kunte, H. K. Roy, A. Taflove, and V. Backman, “Optical methodology for detecting histologically unapparent nanoscale consequences of genetic alterations in biological cells,” Proceedings of the National Academy of Sciences USA (PNAS) 150, 20118-20123 (2008).

  37. H. Subramanian, P. Pradhan, Young L. Kim, and V. Backman, "Penetration depth of low-coherence enhanced backscattering photons in the sub-diffusion regime," Physical Review E 75, 041914-041922 (2007).

  38. M.S. Shahriar, P. Pradhan, G.S. Pati, V. Gopal, and K. Salit, "Light-Shift Imbalance Induced Blockade of Collective Excitations Beyond the Lowest Order," Optics Communications 278, 94-98 (2007).

  39. V. Backman, Y. Kim, Y. Liu, V. Turzhitsky, H. Subramanian, P. Pradhan, H. K. Roy, and M. Goldberg, "Low-coherence enhanced backscattering and its applications," IEEE Eng. Med.  Biol. Soc. 2007, 521-523 (2007).

  40. H. K. Roy, Y. Liu, H. Subramanian, D. Kunte, P. Pradhan, R. K. Wali, J. Koetsier, M. J. Goldberg, Z. Bogojevic, and V. Backman, "Detection of the colorectal cancer (CRC) field-effect through partial wave spectroscopic microscopy (PWS)," Gastroenterology 132, 169-171 (2007).

  41. P. Pradhan, "A model for Quantum Stochastic Absorption in Absorbing Disordered Media," Physical Review B 74, 085107-085111 (2006).

  42. Y. L. Kim, V. Turzhitsky, H. Roy, R. Wali, H. Subramanian, P. Pradhan, and V. Backman, "Low-coherence enhanced backscattering (LEBS): Principles and applications for colon cancer screening," Journal of Biomedical Optics 11, 041125-041134 (2006).

  43. Y.L. Kim, P. Pradhan, H. Subramanian, Y. Liu, M. H. Kim, and V. Backman, "Origin of Low Coherence Enhanced Backscattering," Optics Letters 31, 1459-1461 (2006).

  44. H. Subramanian, P. Pradhan, Y. Kim, Y. Liu, X. Li, and V. Backman, "Modeling Low-Coherence Enhanced Back Scattering Using Monte Carlo Simulation," Applied Optics 45, 6293-6295 (2006).

  45. Y. L. Kim, P. Pradhan, M. H. Kim, and V. Backman, "Circular Polarization Memory Effect in Low-Coherence Enhanced Backscattering of Light," Optics Letters 31, 2744-2746 (2006).

  46. M.S. Shahriar, P. Pradhan, G. Cardoso, V. Gopal, and G. Pati, "Wavelength locking via teleportation using distant quantum entanglement and Bloch–Siegert oscillation," Optics Communications 266, 349-353 (2006).

  47. G. Cardoso, P. Pradhan, and M. S. Shahriar, "In-Situ Observation of the Phase of a Microwave Field using Single-Atom Nonlinear Optics," Physical Review A 71, 063408-063411 (2005).

  48. M.S. Shahriar, P. Pradhan, Y. Tan, M. Jheeta, J. Morzinsky, and P.R. Hemmer, "Demonstration of a Continuously Guided Atomic Interferometer using a Single-Zone Optical Excitation," Journal of the Optical Society of America B 22, 1566-1570 (2005).

    1. Gangat, P. Pradhan, and M.S. Shahriar, "Two-dimensional Nanolithography using Atom Interferometry," Physical Review A 71, 043606-043620 (2005).

  49. M.S. Shahriar, M. Jheeta, Y. Tan, P. Pradhan, and A. Gangat, "Continuously Guided Atomic Interferometry using a Single-Zone Optical Excitation: Theoretical Analysis," Optics Communications 243, 183-201 (2004).

  50. M. S. Shahriar, P. Pradhan, and J. Morzinski, "Determination of the phase of an electromagnetic field via incoherent detection of fluorescence," Physical Review A 69, 032308-032311 (2004).

  51. P. Pradhan and S. Sridhar, "From chaos to disorder: Statistics of the eigenfunctions of microwave cavities," Pramana - Journal of Physics 58, 333-341 (2002).

  52. W. Lu, K. Pance, P.  Pradhan, and S. Sridhar, "Quantum correlations and classical resonances in an open chaotic system," Physica Scripta T90, 238-245 (2001).

  53. P. Pradhan and S. Sridhar, "Correlations due to localization in quantum eigenfunctions of disordered microwave cavities," Physical Review Letters 85, 2360-2363 (2000).

  54. P.  Pradhan and N. Kumar, "Geometric phase for a dimerized disordered continuum: Topological shot noise, " Europhysics Letters 44, 131-136 (1998).

  55. N. Kumar, P. Pradhan, and A. M. Jayannavar, "Statistics of Super-Reflection, "Superlattices and Microstructures 23, 853-858 (1998).

  56. N. Kumar, G. V. Vijayagovindan, and P. Pradhan, "Spin-valve effect in manganese-oxide perovskites: CMR," Giant Magnetoresistance and Related Properties of Metal Oxides, Special Issue, Edited by C.N.R. Rao and B. Raveau (World Scientific Publishing, Singapore, 1998), 305-311 (1998).

  57. P. Pradhan and N. Kumar, "Random Amplifying Media: Mirrorless Laser," Proceedings of the National (Indian) Laser Sciences 17, 70-73 (1997).

  58. P. Pradhan, "Comment on 'The mapping of the Coulomb problem into the oscillator',” by David S. Bateman, Clinton Boyd and Binayak Dutta-Roy, [Am. J. Phys. 60 (9), 833-836(1992)], " Am. J. Phys. 63, 664-664 (1995).

  59. P. Pradhan and N. Kumar, "Localization of light in coherently amplifying random media," Phys. Rev. B 50, 9644-9647 (1994).

  60. N. Tit, P. Pradhan and N. Kumar, "Length-scale-dependent ensemble-averaged conductance of a 1D disordered conductor:  Conductance minimum," Phys. Rev. B 49, 14715-14717 (1994).                                                                                                     

  61. P. Pradhan and N. Kumar, "Suppression of conductance fluctuations in short one-dimensional conductors," Phys. Rev. B 48, 5661-5664 (1993).

  62. P.  Pradhan, M. Arjunwadkar and A. W. Joshi, "Energy Band of One-dimensional Lattice with Two Rectangular Potential Barrier Per Unit Cell," Physics Education (India) 9, 343-348 (1993).  

 

Published Peer-Reviewed Conference Proceedings

 

  1. P. Adhikari, P.K. Shukla, R.K. Rao, P Pradhan. “Photonics probing of probiotics effect on chronic alcoholic brain cell nuclei using light localization via confocal imaging,” Conference on Lasers and Electro-Optics (CLEO), 1-2: Applications and Technology, AM3C, 7 2021

  2. P. Pradhan, P. K. Shukla, S. Bhandari, P. Adhikari, and R. Rao, “Optical study of the structural alteration in hippocampal tissues in chronic stress using partial wave spectroscopy”, SPIE Photonic West, Neural Imaging and Sensing 11226, 67, International Society for Optics and Photonics, 2020.

  3. P. Adhikari, P. Shukla, F. Alharthi, B. Regmi, R. Rao, and P. Pradhan, “Optical Probing of Nanostructural Alterations of Brain Tissues by Partial Wave Spectroscopy in Chronic Alcoholism”, CLEO: Applications and Technology, AM3I.4, 2020.

  4. P. Adhikari, P. Shukla, F. Alharthi, R. Rao, and P. Pradhan, “Spectroscopic study of structural alterations in gut tissues at the nanoscale level due to total body irradiation (TBI)”, Frontiers in Optics, FW1E. 6, 2020.

  5. Prakash Adhikari, Fatemah Alharthi, and Prabhakar Pradhan, "Partial Wave Spectroscopy Detection of Cancer Stages using Tissue Microarrays (TMA) Samples." In Frontiers in Optics, pp. JW4A-89. Optical Society of America, 2019.

  6. H. Subramanian, D. Damania, K. Sholanki, Y. Stypula, L. Cherkezyan, A. Tiwari, P. Pradhan, D. Kunte, H. K. Roy; V. Backman, “Partial Wave Spectroscopy and Its Relation to Nanoscale Disorder in Nuclear Architecture.”  Proceedings of Biomedical Optics (BIOMED), BWB4 (2010).

  7. V. Backman, H. Subramanian, P. Pradhan, Y. Liu, I. Capoglu, J. Rogers, “Detecting Alterations in Cell Nanoarchitecture with Optical Imaging: Implications for Cancer,” Proceedings of Laser Science (LS), LTHD3 (2008).

  8. H. Subramanian, P. Pradhan, D.  Damania, D. Balikov, S.  Maheshwari, V. Backman, “Understanding cell nano-architecture and its alteration in carcinogenesis via partial wave spectroscopy,” Proceedings in Frontiers in Optics, FWV6 (2007).  

  9. H. Subramanian, P. Pradhan, Y.  Kim, and V. Backman, "Depth of penetration of low coherence enhanced backscattering photons in the sub-diffusion regime," Proc. SPIE 6436, 643605 (2007).

  10. Y. Kim, P. Pradhan, V. Turzhitsky, H. Subramanian, Y.  Liu, R. Wali, H. Roy, and V. Backman, "Low-coherence enhanced backscattering of light: characteristics and applications for colon cancer screening," Proc. SPIE 6446, 644606 (2007).

  11. Y. L. Kim, P. Pradhan, H. Subramanian, Y. Liu, M. H. Kim, V. Backman, “Minimal scattering events in enhanced backscattering (EBS) of light: Origin of low-coherence EBS in discrete tissue models,” Proceedings of Photonics Materials. MB5 (2006).

  12. Y. Liu, P. Pradhan, X. Li, Y. L. Kim, R. K. Wali, H. K. Roy, V. Backman, “Partial-Wave Spectroscopy to Detect the Initial Stage of Colon Carcinogenesis” Proceedings of the Biomedical topical Meeting (BIO), TuD1(2006).

  13. H. Subramanian, P.  Pradhan, Y.  L. Kim, Y. Liu, Vadim Backman, "Modeling low-coherence enhanced backscattering (LEBS) using photon random walk model of light scattering," Proc. SPIE, Complex Dynamics and Fluctuations in Biomedical Photonics III; Valery V. Tuchin, Ed., Vol. 6085, p.1-9 (2006)

  14. M.S. Shahriar, G. Pati, V. Gopal, R. Tripathi, G. Cardoso, P. Pradhan, M. Massal, R. Nair, "Precision rotation sensing and interferometry using slow light." Proc. of the Quantum Electronics and Laser Science Conference (QELS), 1457 (2005).

  15. M. S. Shahriar and P. Pradhan, "Fundamental limitation on qubit operations due to the Bloch-Siegert Oscillation," The Proceedings of the 6th International Conference on Quantum Communication, Measurement and Computing (QCMC'02), MIT, Cambridge.  LANL quant-ph/ 0212121(2003).

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